Scientific Thinking & Analysis

> 🔔 Claude Scientific Skills is now Scientific Agent Skills. Same skills, broader compatibility — now works with any AI agent that supports the open Agent Skills standard, not just Claude.

> New: K-Dense BYOK — A free, open-source AI co-scientist that runs on your desktop, powered by Scientific Agent Skills. Bring your own API keys, pick from 40+ models, and get a full research workspace with web search, file handling, 100+ scientific databases, and access to all 166 skills in this repo. Your data stays on your computer, and you can optionally scale to cloud compute via Modal for heavy workloads. Get started here.

> 🎥 Webinar recording — Getting Started with K-Dense BYOK > A hands-on walkthrough of K-Dense BYOK, our free, open-source AI co-scientist that runs locally on your own machine and is powered by Scientific Agent Skills. We cover how to set it up, bring your own API keys, and run real research workflows with these skills. No prior technical experience needed. Watch the recording →

> Stay up to date: Follow K-Dense on X, LinkedIn, YouTube, and Reddit for new skills, release announcements, walkthroughs, research workflow demos, and examples you can use with your own AI agent.

> 📄 Paper: Scientific Agent Skills is described in Scientific Agent Skills: A Library of Procedural Knowledge for Research Agents (arXiv:2609.00065). If you use these skills in your research, please cite the paper.

A comprehensive collection of 166 ready-to-use scientific and research skills (covering cancer genomics, individual-level 1000 Genomes queries, genome-wide precomputed variant effects from the AlphaGenome Atlas, hosted regulatory-sequence prediction, live pathogen-variant surveillance, analytical method validation, PK/PD modelling and dose selection, full-text biomedical and regulatory literature retrieval, drug-target binding, bounded biomedical knowledge graph search, molecular dynamics, RNA velocity, microbiome foundation models, geospatial science, time series forecasting, scientific ML resource discovery via Hugging Science, 78+ scientific databases, and more) for any AI agent that supports the open Agent Skills standard, created by K-Dense. The repository is also a portable Agent Plugins package (plugin.json + skills/), so plugin-capable clients can load the whole collection as one plugin. Works with Cursor, Claude Code, Codex, Google Antigravity, and more. Transform your AI agent into a research assistant capable of executing complex multi-step scientific workflows across biology, chemistry, medicine, and beyond.

> ⭐ Help make AI for science easier to discover: If Scientific Agent Skills saves you time, teaches your agent a workflow, or helps your lab move faster, please star this repository. A star is a public signal that these open, reusable research skills are worth maintaining: it helps scientists, engineers, and open-source contributors find the project, shows which agent-skill standards are gaining real adoption, and gives us a clear reason to keep expanding the collection for the community.

These skills enable your AI agent to seamlessly work with specialized scientific libraries, databases, and tools across multiple scientific domains. While the agent can use any Python package or API on its own, these explicitly defined skills provide curated documentation and examples that make it significantly stronger and more reliable for the workflows below:

• 🧬 Bioinformatics & Genomics - Sequence analysis, single-cell RNA-seq, gene regulatory networks, variant annotation, phylogenetic analysis